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However, the latest 2025 update to the Obesity Canada pharmacotherapy guideline emphasizes that pharmacotherapy should be initiated only after a comprehensive assessment of adiposity and should be personalized according to individual values, preferences, and long-term adherence potential

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But based on the published data, I do not think one can reasonably claim that retatrutide is muscle sparing

Disclaimer: This information is for educational purposes only and is not a substitute for professional medical advice