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What to Expect during and after Your First Semaglutide Injection Common Sensations during the Injection A slight pinch or sting as the needle enters the skin

These can include nausea, digestive changes, or decreased appetite

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Too much slowing: In some people, food can remain in the stomach for longer than normal, leading to reflux, discomfort, or rarely a condition called gastroparesis

Proc Nutr Soc 71:521533