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WS patient samples and WS animal models' NAD+-deficient cells showed impaired mitophagy (selective degradation of defective mitochondria) (25)

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Your provider may recommend behavioral strategies, dietary adjustments, or continued dose progression to support your goals

Body weight and composition play a role, as tirzepatide distributes into tissues, and individuals with higher body weight may have different volumes of distribution

10.1016/j.jep.2024.118870 138 ZhaoJ.ZhouH.AnY.ShenK.YuL

If you need nasal decongestant relief, discuss with your provider whether a topical nasal spray (which bypasses the digestive tract entirely) might be a safer first choice