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A pharmacokinetic analysis of Retatrutide published in the Journal of Clinical Pharmacology reported a mean terminal half-life of approximately 6 days with a coefficient of variation below 30%, supporting reliable weekly dosing in primate models

Drug interactions: Certain medications, such as omeprazole, lansoprazole, cimetidine, and metformin, can lead to low vitamin B12 levels

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[DOI] [PubMed] [Google Scholar] 3.Alhadeff AL

While some trials suggest a connection, more peer review is required to confirm whether oral vitamin B12 supplements or intramuscular injections can prevent fractures

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