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Proviral insertion in murine lymphomas 2 (PIM2) is reported to act as an oncogene in gastric cancer, controlling apoptosis via ROS-triggered ER stress, and promoting the development of gastric cancer (72)

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This Review delineates several of the more common progression trajectories that occur in the patient setting and proposes models for tumour evolution that integrate genetic, histopathological, clinical and biological insights from the melanoma literature

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