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Also, in the experiments on human breast cancer cells, Won and Seo found that the inactivation of PI3K/Akt/mTORC1 signaling pathway promotes the expression of caspases and Bax leading to increased apoptosis [302]

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Glucose, insulin, and PTTs Male C57BL/6J, Glp1r KO, and db/db mice were fasted overnight (18:00 to next 10:00) or for 4 h (9:0013:00) in GTT, for 4 h in ITT, and overnight in PTT

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Women are born with a finite number of oocytes that cannot be replaced, and there is a steady and continuous decline in the ovarian reserve after birth