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As expected monotreme GLP-1 peptides showed significantly less potency than hGLP-1 in assays measuring cAMP accumulation, Ca 2+ mobilization and ERK1/2 phosphorylation acting through both human and platypus receptors (Fig

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For the 9 mg dose, the weight reduction was 26.4%, compared to 2.1% in the placebo group

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Allison Rodgers, an OB-GYN and reproductive endocrinologist at Fertility Centers of Illinois