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However, like all medications, semaglutide comes with a side effect profile that varies widely between individuals

The Lancet Psychiatry , 2026

KD, CW-S, VR, LD, DH, M-CA, DB, AP, OD-C, TB, FRG, UW contributed to data analysis

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To the extent that hyperglycemia contributes to renal injury and nephropathy, the antihyperglycemic effects of long-term DPP-4 inhibition might be expected to slow the rate of decline of glomerular function, if this benefit can be sustained for prolonged periods of time [83, 84]

BELIEVE Study Results: BELIEVE Study Efficacy and Safety Results: Weight Reduction and Body Composition