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[46] After completing the SURPASS-2 trial (NCT03987919), the company announced in April 2022 that tirzepatide had successfully met its clinical endpoints in obese and overweight participants without diabetes

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Retatrutide is a peptide-based compound designed to target metabolic pathways, primarily used for research in metabolic disorders like obesity and insulin resistance

Higher concentrations (1%) also paralyze accommodation (resulting in cycloplegia)

Patients should not stop the tablet and start an injection at a self-selected dose

It was also used to detect -catenin (green) and E-cadherin (red)