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This is also the dose level where the conversation about whether to continue escalating or hold at the current dose becomes medically relevant

Moreover, hypertension resolution was achieved in 23% of those treated with GLP-1 agonists, compared to 11% in the placebo group

Similarly, in primary neurons, we also found that knockdown of A-SYN by siRNA lentivirus mitigated hypoxia-induced neuronal death (Supplemental Fig

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