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Description

The current best estimates are tracked in when will retatrutide be available

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Based on Phase 2 trial data (Jastreboff et al., NEJM , 2023), the most commonly reported adverse effects of retatrutide include: Gastrointestinal effects: Nausea, vomiting, diarrhoea, and constipation (most frequent, particularly during dose escalation) Injection site reactions: Redness, bruising, or mild discomfort Decreased appetite: Generally considered a therapeutic effect but can contribute to nutritional deficiency if severe Increased heart rate: Observed with glucagon receptor agonism

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Rev Endocrine Metab Disord (2022) 23(3):52139

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Originally for Type 2 diabetes , they are now widely used for weight loss and reducing cardiovascular risks in at-risk patients

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38 , S4S14 (2014)

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