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Y1230C and Y1235D mutations consistently promote HNSCC metastasis

doi: 10.1089/ars.2012.4785 26 LambethJD

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It has been well established that the cerebellum is essential for adaptive motor learning, which optimizes the force and timing of individual muscle contractions for accurate movements, and recent studies also suggest a role for the cerebellum in higher-order adaptive control of actions [342]

Further analysis of aged mice testes after FOXO4-DRI treatment revealed a reduction in interstitial SA--gal activity, along with decreased levels of senescence-associated proteins p53, p21, and p16