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4.5 The gut microbiota-ferroptosis axis hypothesis in OA pathogenesis Elaborating on the above research evidence and theoretical conclusions, we postulate this gut microbiota-ferroptosis axis hypothesis to indicate this relationship plays a role in and is a mechanism in the pathogenesis of OA

Stop Consuming Alcohol Consuming alcohol drastically decreases the glutathione level in the overall body, specifically in the lungs

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Metabolic signalling: GLP-1 receptor activation stimulates glucose-dependent insulin secretion and reduces glucagon release, which helps control blood glucose levels

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