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In several RCTs, GLP-1RAs, when used alone or in combination with other hypoglycemic agents including metformin, sulfonylurea, DPP-4 inhibitor, thiazolidinedione, and sodium-glucose cotransporter 2 inhibitor, showed superior or non-inferior blood glucose lowering ability compared to insulin treatment [64,65]

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[DOI] [PubMed] [Google Scholar] 51.Ventafridda V., Fochi C., De Conno D., Sganzerla E