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Published laboratory studies have examined 5-Amino-1MQ as an NNMT inhibitor in experimental models

*Nutrient Reference Value (EU)

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23 NADPH is also needed for dihydrofolate reductase (DHFR) enzyme to catalyze the reduction of dihydrofolate to tetrahydrofolate (THF) in folate metabolism, which is required for de novo biosynthesis of thymidylate, purines, methionine, and some amino acids