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Cell Metab (2009) 9(4):31126

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Compared to both germ-free and antibiotic-administered rodents, commensal microbiota lead to an increased synthesis of neuropeptides, measured indirectly by phosphorylated cAMP response element-binding protein (pCREB), neuropeptide transcripts and protein expression of somatostatin (SST) and cocaine- and amphetamine-regulated transcript (CART) in the ileum and colon

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Individuals with certain genetic profiles may achieve faster weight loss and greater appetite control, while others may require higher doses or combined therapies to reach similar results

The face starts looking leaner