As a major intracellular reductant, GSH directly scavenges reactive oxygen species and supports enzymatic antioxidant defense pathways such as glutathione peroxidase
"l-Carnosine supplementation attenuated fasting glucose, triglycerides, advanced glycation end products, and tumor necrosis factor- levels in patients with type 2 diabetes: a double-blind placebo-controlled randomized clinical trial." National Library of Medicine
On the positive side, weight loss and improved metabolic health often enhance mood, self-esteem, and energy in lupus patients
Diabetes Obes Metab 17:414422 Habegger KM, Heppner KM, Geary N, Bartness TJ, DiMarchi R, Tschop MH (2010) The metabolic actions of glucagon revisited
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