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The body has mechanisms to control most of them, including ergothioneine and glutathione, but eventually enough accrue to cause damage, which has been associated with many of the diseases of aging, like cancer, coronary heart disease and Alzheimers. The amounts of ergothioneine and glutathione in mushrooms vary by species with the porcini species, a wild variety, containing the highest amount of the two compounds among the 13 species tested, the study found

Hippuric acid, a glycine conjugate involved in liver detoxification, showed a decrease post-seizure, likely indicating a depletion of glycine, which also functions as a neurotransmitter in inhibitory signalling in the central nervous system 33