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Breastfeeding The safety of semaglutide during breastfeeding remains uncertain: Injectable Forms (Ozempic, Wegovy): Limited data suggest that semaglutide may be present in breast milk, although its unclear what impact, if any, this might have on a nursing infant

Saxagliptin may also cause urinary tract infections and peripheral edema (3.6% and 6.8%, respectively)

Researchers observed a statistically significant protective effect with GLP-1 use against three specific cancer types: endometrial cancer (HR = 0.75

Stimulant laxatives (like senna or bisacodyl) can be used occasionally, but long-term reliance may reduce effectiveness and cause dependency

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For example, PRMT1-mediated STAT6 methylation, induced by hypoxia-inducible factor (HIF)-1, promoted M2 macrophage polarization, contributing to fibrotic signaling in lung epithelial cells [91]