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9.2 GSH-triggered drug release and prodrug activation strategies GSH-responsive drug delivery and prodrug activation systems often exploit its high affinity for metal ions to trigger selective drug release within the tumor microenvironment (TME)

In vitro studies suggest it may have higher affinity for certain growth factor receptors, but head-to-head human RCT data does not exist as of 2026

1f] were found in frontal cortex of F rats compared to C rats

Luedde M, et al

In addition, lipid peroxidation levels were detected by measuring thiobarbituric acid (TBA)-reactive substances (TBARSs) such as MDA (Satoh, 1978)

Proper consultation is essential before starting treatment