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Over the last 30 years, a number of aberrant biomarkers have been observed in the brain and other biological fluids of children with ASD, corroborating the hypothesis of a bio-energetic deficit in ASD children [14, 68]
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In a 2013 study of the concentrations of trace minerals in 44 individuals newly diagnosed with mild-to-moderate obstructive sleep apnea compared with healthy controls, those with sleep apnea had lower levels of red blood cell selenium and glutathione peroxidase activity than people without apnea, and selenium was negatively associated with AHI values
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