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This conservative approach allows for assessment of individual tolerance before increasing to the 2-5mg range used in more intensive protocols

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Abbreviations ASD: Autism spectrum disorder AlCl3: Aluminium chloride SOD: Superoxide Dismutase CAT: Catalase GSH: Glutathione ROS: Reactive oxygen species PI3K: Phosphoinositide 3Kinase ACHE: Acetylcholinesterase LPO: Lipid peroxidation IAEC: Institutional Animal Ethics Committee TCA: Trichloroacetic acid MDA: Malondialdehyde TBA: Thiobarbituric acid ECD: Electron capture detector OPA: Ophthalaldehyde References Alsubaiei SRM, Alfawaz HA, Bhat RS, El-Ansary A (2023) Nutritional intervention as a complementary neuroprotective approach against propionic acid-induced neurotoxicity and associated biochemical autistic features in rat pups

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