Orlistat and cyclosporine should not be simultaneously co-administered Patients should be strongly encouraged to take a multivitamin supplement that contains fat-soluble vitamins to ensure adequate nutrition because Orlistat has been shown to reduce the absorption of some fat-soluble vitamins and beta-carotene Rare cases of severe liver injury with hepatocellular necrosis or acute hepatic failure have been reported, with some of these cases resulting in liver transplant or death Patients may develop increased levels of urinary oxalate following treatment with Orlistat
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Notably, randomized controlled trials have revealed that TCM interventions reduced mortality rates, shortened hospitalization duration, and mitigated postoperative complications in AP patients compared to conventional therapies ( Chaiqinchengqi decoction treatment reduced the duration of 28-day respiratory failure (median: 1.0 days, 95% confidence interval: 2.0 to 0.0) and improve 6-month clinical outcomes in AP patients compared with the placebo ( Dachengqi decoction , as adjunctive therapy, reduced multiple organ dysfunction syndrome incidence by 40% and pancreatic infection risk by 5% in severe AP patients ( Tongfu powder treatment alleviated gastrointestinal dysfunction in AP cohorts ( vs
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