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High androgen and low progesterone Polycystic ovary syndrome (PCOS) is often characterized by high levels of androgens or male hormones, low progesterone and insulin resistance

Recently, it was reported that macrophage-derived TNF- enhanced PFKFB3-driven glycolysis and lactate production in fibroblasts [35]

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But here is where the narrative starts to fall apart when you look more carefully