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Description

To determine whether Ssu72 functions as a phosphatase for GSK3, purified GST-GSK3 was phosphorylated by recombinant AKT and then incubated with purified His-Ssu72 (WT) or His-Ssu72 phosphatase-dead mutant (C12S) proteins (Supplementary Fig

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In this study, the authors used insulin detemir at a dose of 20 units twice daily in the intervention group

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