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So, the researchers set out on a molecular fishing expedition in a pancreatic beta cell line

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Hepatol Res 45(3):269278 [DOI] [PubMed] [Google Scholar] Errafii K, Khalifa O, Al-Akl NS, Arredouani A (2022) Comparative transcriptome analysis reveals that Exendin-4 improves steatosis in HepG2 cells by modulating signaling pathways related to lipid metabolism

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In order to clone the GLP-1 receptor Thorens drew on the expertise that he had picked up from cloning the GLUT2 gene which encodes for a protein that helps to transport glucose across cell membranes