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Insulin produced in excessive amounts that has lost its function increases inflammation in the body and promotes weight gain

Serotonin predominantly produces these effects by direct agonism of the various serotonin receptors found throughout the body

These trials compared cardiovascular outcomes in large groups of patients (5,000 to 16,000) treated with DPP4i versus placebo over approximately 1.5 to 6 years

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ATF4 protects the heart from failure by antagonizing oxidative stress

McPhee, Selena Singh, and Katherine M