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When p53 is inactivated, the accumulation of DNA damage leads to sustained senescence induction through p16 expression 29

Under oxidative stress, GSH can be converted into the oxidized form (glutathione disulfide, GSSG) to protect cells from the oxidative stress and assist to capture free radicals that can injure RNA and DNA 7,8,9

Twamley SG, Stach A, Heilmann H, Shl-Kielczynski B, Stangl V, Ludwig A, Mnster-Wandowski A

Slower recovery, stubborn body fat, decreased energy, and poor sleep are classic signs of age-related growth hormone decline

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Evidence for its initiation of stress signaling pathways that promote endogenous antioxidant capacity