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Glucagon like peptide-1 promotes satiety and suppresses energy intake in humans

Researchers keep this compound for lab studies only

Low Wang said doctors and researchers still do not fully understand why activating these receptors is so effective in causing weight loss

By reducing hunger (and ameliorating the constant sense of deprivation often experienced with decreased portion sizes), prolonging the feeling of fullness after eating and, preventing over-eating, and reducing high-fat/ sugar cravings due to their natural effect on the brains reward system, they support gradual and sustainable weight loss when combined with dietary and lifestyle changes

But for people who hate needles, these medications hold a glaring, obvious drawback: They require taking a weekly shot

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