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The deficiency is also common in people who follow a vegetarian or vegan diet, as B12 is only found naturally in animal foods

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Although the amount of cyanide in cyanocobalamin is small, individuals with compromised detoxification pathways may benefit more from Methylcobalamin

Estrogen receptor activation in bone counters osteoclastic resorption, thereby potentially slowing bone mineral density loss that accelerates after natural or surgical menopause