While some side effects, such as a decrease in the levels of potassium (hypokalemia) by VitC may be mitigated by supplementing the formula, certain conditions have to be closely monitored and may be contraindicative for IVC treatment
"An mRNA splice variant of the AFX gene with altered transcriptional activity"
The other calms things down
PubMed, Saleh, Rofida A., et al

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GN-induced ARF is characterized by rapid deterioration of kidney function, increased SCr and BUN levels, and albuminuria 2