Hormonal changes that initially suppress appetite may diminish over time, whilst anatomical alterations to the gastrointestinal tract can gradually accommodate larger food volumes
In a single piece, he concisely captures: the state of the field the most important clinical trials where the pipeline is headed These Clinical trials are raising the bar and expanding future treatment options: Retatrutide ~24% weight loss (triple agonist) MariTide 1216% weight loss (GLP-1 + GIP antagonist) CagriSema up to 20% weight loss + ~2% HbA1c drop Orforglipron oral GLP-1, HbA1c 1.5%, weight 7.6% IcoSema weekly semaglutide + once-weekly insulin Even more exciting
This may be further pronounced in patients with diabetes with compromised gastrointestinal function due to autonomic neuropathy
Link: Precision Telemed Clickable Links Compounded Tirzepatide Compounded Semaglutide Sermorelin Peptide NAD+ Injections Testosterone Replacement Therapy Hair Loss Erectile Dysfunction
Retatrutide is being developed by Eli Lilly and Company, the same manufacturer behind tirzepatide (Mounjaro)
Set the vial down on your clean surface