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[1] [4] If swelling occurs while taking a GLP-1 agonist, it is important to consider alternative explanations, including: Concurrent medications (e.g., calcium channel blockers, NSAIDs) Underlying cardiac, renal, or hepatic conditions Dietary changes or increased salt intake Venous insufficiency or lymphatic issues Patients experiencing unexplained swelling should not automatically attribute it to their GLP-1 medication without proper clinical assessment, as other potentially serious causes must be excluded

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Bronchoscopy on Day 6 revealed diffuse erythema and mucosal changes in the posterior trachea suggestive of reflux injury

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24 In overweight/obese non-diabetic subjects with cardiovascular disease, the Semaglutide Effects on Cardiovascular Outcomes in People with Overweight or Obesity (SELECT) trial showed a 20% reduction in MACE, as well as reduced incidence of nonfatal myocardial infarction and stroke

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