The assay is based on the conversion of citrate to isocitrate, to -ketoglutarate, which results in the production of NADPH
As regards its mechanism of action, in some cell lines Que was able to inhibit the production of TNF in macrophages (Tang et al., 2019), IL-8 in A549 lung cells induced by lipopolysaccharide (LPS) (Geraets et al., 2007), and TNF- and IL-1 mRNA levels in glial cells, causing a decrease in neuronal cell death induced by microglial activation (Li et al., 2016)
Use along with a good multi-vitamin, multi mineral supplement
While Vitamin B12 tablets are readily available, easy to use (you just pop it in your mouth!), and cheaper, the rate at which the vitamin absorbs in tablet form is relatively slow
This comes after several prior warnings
Available for UK laboratory research