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The pathophysiology of ROS cannot be understood without considering their crosstalk with other reactive speciesnitrogen (RNS), sulfur (RSS) and carbonforming an interconnected redox network (Cortese-Krott et al

2005;138A(3):2827

Functional characterization of CYP2C8.13 and CYP2C8.14: catalytic activities toward paclitaxel

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These were predominantly mild to moderate, transient, and most frequent during dose escalation