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BMJ 367 , l6217 (2019)

doi: 10.1097/INF.0000000000004326

I lost 60 pounds

The 3/6mg group is an odd duck and I wish theyd have just had a 6mg arm, as clearly 3mg alone rapidly plateaus off, but the 6mg kick started the weight loss again

The addition of glucagon receptor activation in retatrutide, combined with GIP, creates a metabolic environment that simultaneously improves insulin sensitivity, enhances appropriate insulin secretion, and increases energy expenditure