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One set of measurements on a single day does not tell the clinician that the dog's heart is enlarged , because the clinician does not know whether or not the heart ever was smaller than it is on the single day it was measured

Nature (2013) 496:44555

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The initial side effects of tirzepatide usually surface during the first week of treatment

Vancomycin is an antibiotic that is not absorbed when taken orally, but is administered orally to treat colitis (GI infection) caused by conditions that allow the overgrowth of vancomycin-sensitive Clostridium difficile within the intestine