Additionally, direct supplementation of monounsaturated fatty acids (MUFAs) in the diet to replace PUFA, which is prone to lipid peroxidation on cell membranes, can prevent the accumulation of lipid ROS and the occurrence of ferroptosis [295]
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However, dietary sources alone may not be enough to maintain optimal levels, especially for people exposed to high levels of stress or toxins
If IGF-1 exceeds 3 standard deviations above the age-adjusted mean, reduce dose or discontinue