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Clinical trials demonstrate a dose-dependent relationship, with higher doses producing greater weight reductionup to 20.9% at 72 weeks with the 15 mg dose

Freezing reconstituted tirzepatide damages the peptide

Lower doses usually work well only for maintaining the goal weight

Semaglutide works firstly by slowing the emptying of the stomach and signaling the brain to feel full sooner, thus reducing caloric intake

However, individual reactions can vary, and some patients may experience it as part of their response to the medication

The trial also enabled up to 85.1 percent of participants to reduce their body weight by 5 percent, versus 38.8 percent with placebo