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How This Works TB-500 mimics endogenous thymosin 4, modulating inflammation and activating repair pathways including PI3K/Akt and Notch signaling to enhance angiogenesis and cell migration [1] [2]

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If, however, you're designing a study specifically to test the local gut effects of peptides, then an oral formulation might be your test article, but you'd be doing so with the full understanding of its limitations