Fatigue (week 1-2) : Your body is switching fuel sources
Compared with similar households with no reported GLP-1 use, people on GLP-1s spent less on their grocery bill, particularly on snack foods
Mechanism of action of GLP-1 receptor agonists: Direct receptor binding These medications bind specifically to GLP-1 receptors on pancreatic beta cells, stimulating insulin secretion in a glucose-dependent manner (meaning they work when blood glucose is elevated)
Expression of GLP-1 receptors in the ocular region While the pharmacokinetic properties of GLP-1RAs determine their systemic availability, their therapeutic potential in ocular diseases is fundamentally contingent upon the presence and localization of GLP-1 R in target tissues
For example, 10 mg in 2 mL equals 5 mg/mL or 5,000 mcg/mL
Slowing down this process makes us feel fuller for longer, leading to lower calorie intake