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Our bodies are wired for survival, not modern life

potentially leading to prolonged gaps in therapy and a meaningful compromise in treatment efficacy

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Finally, the references of relevant articles were screened

It is considered a multi-target agent that addresses metabolic dysfunction at its root by modulating gene expression and cellular signaling pathways

Besides Bacteroidetes and Firmicutes constitute over 49% of the healthy gut bacterial population (Qin et al., 2010)