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The vial becomes a contamination risk after the first use

An in vivo study in rabbits has shown that BSS PLUS is more suitable than normal saline or Balanced Salt Solution for intravitreal irrigation because BSS PLUS contains the appropriate bicarbonate, pH, and ionic composition necessary for the maintenance of normal retinal electrical activity

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Although HTY is often described as a multitarget compound, most available studies report pathway modulation based on downstream markers rather than direct target binding