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Small-molecule inhibitors of STAT3 selectively kill AML stem cells and preserve normal hematopoietic cells

[7] [8] NAD+ and NADH are continuously recycled during redox reactions, but during other metabolic activities, they are absorbed by NAD+-dependent enzymes and may subsequently become depleted over time, increasing the risk of DNA damage, age-related illnesses, and mitochondrial malfunction

They reduce toxic peroxides such as hydrogen peroxide and lipid hydroperoxides by reacting with glutathione

Shuster 2008

Furthermore, by lowering inflammation in the body, it can help reduce symptoms of some conditions