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Short-chain fatty acids ameliorates lipid profile, oxidative stress and inflammation in letrozole induced polycystic ovary syndrome rat model

In animal models, it upregulates the anti-apoptotic protein Bcl-2, downregulates the pro-apoptotic protein Bax, alters mitochondrial membrane permeability, and inhibits the activation of executioner caspases such as caspase-3, thereby blocking the apoptotic signaling pathway ( 3.4 Immunomodulatory mechanisms Glycyrrhizin exhibits multiple immunomodulatory mechanisms

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After centrifugation, 300 L PBS was added to resuspend cells, followed by the addition of 700 L pre-cooled anhydrous ethanol drop by drop, and incubated at 4 for 1824 h

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Alpha-MSH modulates local and circulating tumor necrosis factor-alpha in experimental brain inflammation