(He won the men's open division of the New York Pro 2025 bodybuilding competition in May.) Derek Munro, the bodybuilder who produces the podcast "More Plates More Dates" and has appeared on Joe Rogan's podcast, was another early pioneer
GLP-1 receptors control appetite and gastric emptying
If a chunk of your weight loss comes from muscle rather than fat, you can hit your goal weight while ending up "skinny-fat" , lighter, but softer and weaker than you wanted
Storage and handling impact on injection comfort Improperly stored compounded tirzepatide can develop particulates, pH changes, or degradation products that irritate injection sites
Among the mechanisms, our research group and others have demonstrated that the gut microbiota fermentation (i.e., bacterial digestion of specific compounds) of specific prebiotics or other non-digestible carbohydrates is associated with the secretion of enteroendocrine peptides, such as the glucagon-like peptide-1 (GLP-1) and peptide YY (PYY), produced by L-cells
One-time prescribing has less value when tolerability and refill timing remain unresolved