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2020;37(8) Colitti M, Gaspardo B, Della Pria A, Scaini C, Stefanon B

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found that the abundance of mitochondrial Asp in T cells in rheumatoid arthritis (RA) was decreased, which inhibited NAD + turnover, resulting in a decrease in NAD + /NADH ratio and a reduction in ADP-ribosylation of proteins which is NAD + dependent

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1 Cait J., Hughes M.R., Zeglinski M.R., Chan A.W., Osterhof S., Scott R.W., Hernaez D.C., Cait A., Vogl W., Bernatchez P., Underhill T.M., Granville D.J., Murphy T.H., Roskelley C.D