Dupixent (sBLA), February 28 Sanofi For adults and children aged 6 years and older with allergic fungal rhinosinusitis
Because GLP-1 agonists provide sustained, long-acting receptor stimulation, they steadily quiet the neurochemical dopamine spikes associated with substance triggers
A prescriber will often start a patient off with the lowest initial dose (2.5mg) once a week for four weeks
Ongoing monitoring and tailored interventions are critical, especially as patients may experience fluctuating weight or continued treatment with GLP-1 RAs
The injectable form maintains a slight consistency advantage due to more predictable pharmacokinetics, but the oral pill is a clinically validated and highly effective option, particularly for needle-averse patients
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