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For clinics that use or emphasize compounded drugs, availability can vary by state and pharmacy, and compounded GLP-1s are not FDA approved

Furthermore, the osteoprotegerin (OPG)/Receptor Activator of Nuclear Factor B Ligand (RANKL) pathway is regulated by GLP-1RAs, increasing the OPG/RANKL ratio to inhibit osteoclast formation and promote bone formation by upregulating osteogenic genes like OC, COL1, Runx2, and ALP [120, 121]

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If the body learns to rely on an exogenous source, it could potentially stop producing it on its own, therefore when you go off the drugs it could potentially make the problem worse than when you started

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Injectable pens and needles should be disposed of in FDA-cleared sharps containers, never in household trash or recycling