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These results suggest that the angiopoietin 2-mediated astrocyte apoptosis induced by high glucose levels occurs through the v5-integrin/glycogen synthase kinase-3/-catenin signaling pathway

Personal and family medical history, especially with heart disease

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Tirzepatide should not be used in people with a personal or family history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN2)

The addition of a ghrelin mimetic may also aid through other ghrelin-related actions, including neuroprotection

The anaesthetist, opioid analgesic drugs, and serotonin toxicity: a mechanistic and clinical review